Congratulations to Dr. Zach Ferraro for being awarded a CIHR Travel grant to present his work, “Maternal lipid metabolism correlates with surrogate markers of insulin-like growth factor bioavailability in maternal and umbilical cord serum” at the Canadian Obesity Summit in...Read More
Search Results for: Ferraro
A paper by Dr. Zachary Ferraro and his colleagues, “Role of leptin in pregnancy: Consequences of maternal obesity,” was recently published ahead of print in Placenta. Citation information is below. Tessier DR, Ferraro ZM, Gruslin A. Role of leptin in pregnancy: Consequences of maternal obesity. Placenta. 2013 Jan 16. pii: S0143-4004(12)00470-5. doi: 10.1016/j.placenta.2012.11.035. [Epub ahead of print] ABSTRACT: Maternal obesity is associated with increased risks of pregnancy complications. Excessive fat mass, common to obese women, has the potential to influence production and secretion of adipose tissue derived proteins called adipokines. The adipokine leptin is involved in the regulation of multiple aspects of maternal metabolic homeostasis. In addition, leptin has been shown to be important for placentation and maternal-fetal exchanges processes regulating growth and development. In later stages of a healthy pregnancy, central leptin resistance occurs to allow increased nutrient availability for the fetus. Disruption of the signaling capacity of leptin associated with obesity is emerging as a potential risk factor leading topregnancy complications as a result of aberrant fuel partitioning in utero. In this review we discuss the influence of obesity on the roles of leptin andleptin resistance at the central and placental...Read More
Dr. Zachary Ferraro’s Dissertation Abstract Published in Applied Physiology, Nutrition and Metabolism
Dr. Zachary Ferraro’s dissertation abstract titled, “An examination of maternal contributors and potential modifiers of fetal growth in pregnancy,” has been published in Applied Physiology, Nutrition and Metabolism. Citation details are below. Zachary M Ferraro. An examination of maternal contributors and potential modifiers of fetal growth in pregnancy. Applied Physiology, Nutrition, and Metabolism, 10.1139/apnm-2012-0426. Published on the web 19 November 2012. ABSTRACT: A greater understanding of critical periods of body weight regulation, including pregnancy, may aid in efforts to optimize weight management strategies for the mother and her baby. The gestational period has been implicated to play, in the child, a vital role in the developmental origins of obesity and other cardiometabolic diseases later in life. Therefore, we initially examined existing literature on the role of maternal obesity and its link to pediatric obesity and documented the known underlying physiological mechanisms responsible for this relationship while suggesting potential intervention targets that may improve maternal-fetal outcomes. In a second paper, we aimed to quantify maternal predictors of large for gestational age neonates in the Ottawa and Kingston (OaK) birth cohort with specific hypotheses verifying the independent contribution of maternal prepregnancy body mass index (BMI) and excessive gestational weight gain (GWG) to fetal overgrowth. This paper also highlights the clinical utility of the revised 2009 Institute of Medicine GWG guidelines and discusses the potential role of physiological factors underlying the observed...Read More
Drs. Zach Ferraro and Kristi Adamo (Research Scientist) co-authored an editorial that was recently published in the British Journal of Sports Medicine titled, “An active pregnancy for fetal well-being? The value of active living for most women and their babies.” Citation details are below. Zachary M Ferraro, Andree Gruslin, Kristi B Adamo. An active pregnancy for fetal well-being? The value of active living for most women and their babies. Br J Sports Med...Read More
Dr. Zachary Ferraro authored an article that recently appeared in Hospital News titled, “The Power of Prevention in the Early Years.” From the article: The battle against child obesity is a high priority in Canada not only from a population health perspective, but from the health care system’s economic perspective as well. Moreover, obesity tracks very closely from childhood to adolescence to adulthood meaning that if you have trouble maintaining a healthy weight as a child you are likely to struggle with these very same issues throughout life. Click here to read the article in...Read More
The Healthy Active Living and Obesity Research Group (HALO) was established in 2007 in response to the escalating obesity crisis and the increasing complexity of related co-morbidities. Today the HALO team consists of 17 staff (including 6 researchers), a childhood obesity clinical team (Centre for Healthy Active Living), 17 graduate students, and many community volunteers. Since its inception in 2007, HALO has received over $12 million in research funding; produced more than 520 peer-reviewed publications; has given more than 980 scholarly presentations locally, nationally and internationally; and secured more than 1.3 billion media impressions!