Dr. Mark Tremblay is co-author on a paper, “Do sugar-sweetened beverages cause adverse health outcomes in adults? A systematic review protocol,” that was recently published in Systematic Reviews. Citation details and a summary of the paper are below.
Hamel C, Stevens A, Singh K, Ansari MT, Myers E, Ziegler P, Hutton B, Sharma A, Bjerre LM, Fenton S, Lau DCW, Oâ€™Hara K, Reid R, Salewski E, Shrier I, Willows N, Tremblay M, Moher D. Do sugar-sweetened beverages cause adverse health outcomes in adults? A systematic review protocol. Systematic Reviews 2014; 3:108.
ABSTRACT:Â Background. Chronic diseases, such as cardiovascular disease and type 2 diabetes, impose significant burden toÂ public health. Most chronic diseases are associated with underlying preventable risk factors, such as elevated bloodÂ pressure, blood glucose, and lipids, physical inactivity, excessive sedentary behaviours, overweight and obesity, andÂ tobacco usage. Sugar-sweetened beverages are known to be significant sources of additional caloric intake, andÂ given recent attention to their contribution in the development of chronic diseases, a systematic review isÂ warranted. We will assess whether the consumption of sugar-sweetened beverages in adults is associated withÂ adverse health outcomes and what the potential moderating factors are.Â Methods/Design. Of interest are studies addressing sugar-sweetened beverage consumption, taking a broadÂ perspective. Both direct consumption studies as well as those evaluating interventions that influence consumption (e.g. school policy, educational) will be relevant. Non-specific or multi-faceted behavioural, educational, or policyÂ interventions may also be included subject to the level of evidence that exists for the other interventions/exposures.Â Comparisons of interest and endpoints of interest are pre-specified. We will include randomized controlled trials,Â controlled clinical trials, interrupted time series studies, controlled before-after studies, prospective and retrospectiveÂ comparative cohort studies, case-control studies, and nested case-control designs. The MEDLINEÂ®, Embase, TheÂ Cochrane Library, CINAHL, ERIC, and PsycINFOÂ® databases and grey literature sources will be searched. TheÂ processes for selecting studies, abstracting data, and resolving conflicts are described. We will assess risk of biasÂ using design-specific tools. To determine sets of confounding variables that should be adjusted for, we haveÂ developed causal directed acyclic graphs and will use those to inform our risk of bias assessments. Meta-analysisÂ will be conducted where appropriate; parameters for exploring statistical heterogeneity and effect modifiers areÂ pre-specified. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach willÂ be used for determining the quality of evidence for outcomes.
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