Dr. Gary Goldfield, a Clinical Scientist with HALO, has published a new paper in Applied Physiology, Nutrition and Metabolism, “Gender differences in the effects of methylphenidate on energy intake in young adults: a preliminary study.” Dr. Jean-Philippe Chaput, a Junior Research Chair with HALO, was also an author on the paper. Full citation details are below.
Goldfield GS, Lorello C, Cameron J, Chaput JP. Gender differences in the effects of methylphenidate on energy intake in young adults: a preliminary study. Appl Physiol Nutr Metab. 2011 Oct 27. [Epub ahead of print]
ABSTRACT: The present study examined gender differences in response to methylphenidate (MPH) on energy intake and macronutrient preference. Twelve adults (6 men, 6 women) were given placebo or short-acting MPH (0.5 mg/kg) in a randomized, double blind, placebo-controlled crossover fashion. One hour after drug administration, appetite sensations and the relative reinforcing value of energy-dense snack food were measured, followed immediately by energy intake and macronutrient preference during a buffet lunch. Relative to placebo, men exhibited a significantly greater reduction in energy intake, fat intake, and carbohydrate intake after MPH administration compared with women. Future research is needed to verify these initial findings.